Schizophrenia
Conditions
Brief summary
This study examined the efficacy of an integrative cognitive remediation program (REHACOP) to improve cognition, social cognition, clinical symptoms and functional outcome in patients with schizophrenia.
Interventions
BEHAVIORALREHACOP
REHACOP group consists of 90-minute-long sessions 3 days per week. Specifically, REHACOP group remediation consisted of: Attention unit (4 weeks) training sustained, selective, alternant and divided attention; Memory unit (3 weeks) focusing on visual and verbal learning, recall and recognizing memory; Language unit (3 weeks) including grammar, syntax, vocabulary, verbal fluency, verbal comprehension, abstract language; Executive functions unit (2 weeks) training cognitive planning, proverbs, analogies; and Social cognition unit (1 week) exercising theory of mind, social reasoning and moral dilemmas
BEHAVIORALOccupational activities
Occupational group activities conducted included drawing, gardening, reading the daily news and constructing using different materials (such as paper or wood).
Sponsors
University of Deusto
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* diagnostic criteria for Schizophrenia according to American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)
Exclusion criteria
* evidence of alcohol or drug abuse in the last 30 days * previous history of significant lack of consciousness * mental retardation * relevant neurological or medical condition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in verbal memory after receiving cognitive remediation | 4 months | Verbal memory performance was assessed with the Hopkins Verbal Learning Test-HVLT (Brandt and Benedict 2001) |
| change in processing speed after receiving cognitive remediation | 4 months | Processing speed was assessed with Digit Symbol subtest from Wechsler Adult Intelligence Scale-III (Wechsler 1997) |
| Change in functional competence after receiving cognitive remediation | 4 months | functional competence was measured with San Diego UCSD Performance-Based Skills Assessment- UPSA |
| Change in global functioning after receiving cognitive remediation | 4 months | global functioning measured with Global Assessment of Functioning (GAF) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in emotion perception after receiving cognitive remediation | 4 months | emotion perception was assessed with Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT) |
| change in clinical symptoms after receiving cognitive remediation | 4 months | Clinical symptoms was measured with Positive and Negative Syndrome Scale (PANSS) |
| change in social perception after receiving cognitive remediation | 4 months | Social perception was assessed with the Social Featuring Recognition Test (SFRT) |
| change in theory of mind after receiving cognitive remediation | 4 months | Theory of mind was assessed with Happe Strange Stories Test |
Countries
Spain
Outcome results
None listed