Binge Drinking
Conditions
Brief summary
The purpose of this study is to specify the psychological, cognitive, neuro-functional and genetic profile associated with binge drinker behaviors among young adults. Results will help identifying more precisely vulnerability factors associated with this pattern of alcohol consumption and guiding prevention efforts.
Detailed description
Binge drinking behavior is characterised by speed of drinking on a particular occasion, frequency of drunkenness during the most recent six month period, and the percentage of times getting drunk when drinking. The prevalence of weekly binge drinking among European Union drinkers in 2009 was reported to be 28% of the student population, and 33% among all young people aged 15-24. The consequences of this behavior are multiple and often dramatic, they include: academic failure, violent acts, rape, domestic or road accidents. The study aims to identify vulnerability factors associated with binge drinking. The protocol explores the psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI) patterns associated with binge drinking behavior.
Interventions
OTHERAlcoolpredict
psychological (personality), neuropsychological (executive functions, memory), genetic (snp polymorphisms) and neuro-anatomical (fMRI)
Sponsors
CHU de Reims
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
Yes
Inclusion criteria
: * Males or females * Right-handed * Aged 18-25 years * Native French speaker, able to read French and complete study evaluations * Caucasian * Able to provide informed written and verbal consent
Exclusion criteria
* A significant general medical illness, including neurological disorders, mental retardation or head trauma * Depression, bipolar disorder, schizophrenia or schizoaffective disorder diagnostic according to DSM-IV * Handling of psychotropics substances * A sensorial impairment (visual and/or hearing) * Women who are pregnant * Contraindication to the use of MRI (pacemaker, metal in their body)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuropsychological test : Mini International Neuropsychiatric Interview (M.I.N.I) | day 1 |
| Neuropsychological test : Wisconsin Card Sorting Test (WCST) | V2(3 weeks later) |
| Genetics tests (Single Nucleotide Polymorphism) | V2(3 weeks later) |
| MRI - signal BOLD (" Blood Oxygen Level Dependant "). | V3(up to 2 month) |
| Neuropsychological test : Family Informant Schedule and Criteria (FISC) | day 1 |
| Neuropsychological test : Alcohol Use Questionnaire | day 1 |
| Neuropsychological test :Trail Making Test, partie A et B | V3(up to 2 month) |
| Neuropsychological test : Plus/Minus Test | V3(up to 2 month) |
| Neuropsychological test :Go/No-Go | V3(up to 2 month) |
Countries
France
Outcome results
None listed