Breast Cancer
Conditions
Keywords
hormone replacement therapy, breast cancer, follow up
Brief summary
Non-persistence to adjuvant hormonal therapy for breast cancer at 5 years decrease its efficacy. The objective of this study is to know the women experience (persistence, treatment changes, quality of life) and its determinants, in a french population.
Interventions
OTHERquestionnary of quality of life
Sponsors
Institut de Cancérologie de Lorraine
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients following-up in the Lorraine Institute of Oncology at 5 years of the beginning of an adjuvant hormonal therapy * Women with breast invasive carcinoma positive-RH and indication of adjuvant hormonal therapy * Adult patients * Being capable and agree to follow the study procedure * Patients informed and non-opposed * Covered by social security
Exclusion criteria
* History of other cancer except basal cell carcinoma * Patients with breast invasive carcinoma negative-RH * Synchronous metastases * Relapsed * Previous adjuvant hormonal therapy * Men * Patients with guardianship
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Factors associated with persistence to hormone therapy for breast cancer | 1 day | Women will be classed as persistent if they don't discontinue or abandon hormone therapy during the 5 years after the introduction of the medication. The information will be recorded thanks to a self-questionnary fulfilled the inclusion day. The baseline characteristics will be compared between persistent women and non-persistent women. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of the quality of life | 1 day | Quality of life between patients who continued hormone therapy for 5 years and patients who discontinued treatment early will be searched for using the questionnaire |
| Proportion of women with a change in their treatment | 1 day | Proportion of women who have changed treatment within 5 years following the placing on hormone therapy and reasons for the change. |
| Cause of treatment discontinuation | 1 day | In the subgroup of women who stopped hormone therapy within 5 years following the hormone therapy, determination of the treatment discontinuation. |
| Continued homonotherapy | 1 day | In the subgroup of women who have been treated with hormone therapy for 5 years, determine the proportion of women not opposed to the continuation of hormone therapy beyond 5 years |
Countries
France
Outcome results
None listed