Role of Hyaluronic Acid in the Prevention of Post-operative Adhesions: a RCT

Is Hyaluronic Acid Effective in the Prevention of Post-operative Adhesion?

Status

UNKNOWN

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02790177

Acronym

HiB

Enrollment

150

Registered

2016-06-03

Start date

2016-06-30

Completion date

2017-12-31

Last updated

2016-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Operative Adhesions

Brief summary

The objective of study is to determine the effect of hyaluronic acid on the formation of post-operative adhesions. It will be a randomized control trial comparing the product against normal saline.

Interventions

DRUGHyaluronic Acid

DRUGNORMAL SALINE

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

12 Years to No maximum

Healthy volunteers

Inclusion criteria

\- All consenting patients between the ages of 12-80, who undergo exploratory laparotomy and stoma formation

Exclusion criteria

Previous history of abdominal surgery History of peritoneal dialysis Patients in whom permanent stoma is formed \-

Design outcomes

Primary

Measure	Time frame
POST OPERATIVE ADHESIONS TO BE EVALUATED BY LAPAROSCOPY AT THREE MONTHS INTERVAL	3 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026