Unilateral Vocal Cord Lesions
Conditions
Brief summary
Patients undergoing vocal cord surgery (phonosurgery) are often prescribed voice rest postoperatively. However, no clinical trials have ever been conducted to ascertain the efficacy of using voice rest and its impact on functional voice outcomes. The purpose of this randomized-clinical trial is to determine if the prescription of voice rest has an impact on voice outcomes following phonosurgery.
Detailed description
The study will seek to determine if a 7-day period of absolute voice rest alters voice-related quality of life following phonosurgery
Interventions
BEHAVIORALAbsolute Voice Rest
Patients will be instructed to not use their voice and minimize any voice-use activities such as coughing or throat-clearing for a period of 7 days following surgery.
Sponsors
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Age greater than 18 years * Unilateral vocal cord lesion * Consented for phonosurgery
Exclusion criteria
* Age less than 18 years * Bilateral vocal cord lesions * Prior vocal cord surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Voice Handicap Index (VHI)-10 | 4 weeks post-operative |
Secondary
| Measure | Time frame |
|---|---|
| Frequency perturbation (jitter) | 4 weeks post-operative |
| Amplitude perturbation (shimmer) | 4 weeks post-operative |
| Fundamental frequency | 4 weeks post-operative |
| Maximum phonation time | 4 weeks post-operative |
| Perceptual grading of voice using the Grade, Roughness, Breathiness, Asthenia, Strain, Instability (GRBASI)-scale | 4 weeks post-operative |
Countries
Canada
Contacts
Primary ContactKevin Fung, MD, FRCSC
Outcome results
None listed