Pancreatic Ductal Adenocarcinoma
Conditions
Keywords
Standard lymphadenectomy, extended lymphadenectomy, pancreaticoduodenectomy
Brief summary
The purpose of this study is to compare outcomes of patients undergoing standard or extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer
Interventions
PROCEDUREPancreaticoduodenectomy with Standard lymphadenectomy
Pancreaticoduodenectomy：child's digestive reconstruction standard lymphadenectomy: No 5 6 8a 12b1 12b2 12c 13a 13b 14a 14b 17a 17b
PROCEDUREPancreaticoduodenectomy with Extended lymphadenectomy
Pancreaticoduodenectomy：child's digestive reconstruction extended lymphadenectomy: No8p 12a 12p 14c 14d 16
Sponsors
Shanghai Zhongshan Hospital
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Ruijin Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Pathologic diagnosis of pancreatic ductal adenocarcinoma * Signed the informed consents
Exclusion criteria
* Pathologic diagnosis of other pancreatic cancers * Pre-operative anti-cancer treatment * Recurrence patients * Patients with contraindication(hepatic/ respiratory/ renal dysfunction, etc ) * Pre operative exam: Total bilirubin more than 250µmol/L * AJCC stage IV * Operation non radical
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality | 3yrs post-operation |
Secondary
| Measure | Time frame |
|---|---|
| all-cause mortality | 1yr post-operation |
Countries
China
Outcome results
None listed