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Variations in Anesthesia Care for Hip Fracture Surgery

Sources of Variation in Anesthesia Care for Hip Fracture Surgery and the Association With Outcomes

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02787031
Enrollment
107317
Registered
2016-06-01
Start date
2002-04-30
Completion date
2016-05-31
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Fractures, Anesthesia, Death

Keywords

hip fracture, geriatric, epidemiology, practice variation, anesthesia

Brief summary

The investigators will use health administrative data to examine the variation of anesthesia type for hip fracture surgery, as well as sources of variation and predictors of variation.

Detailed description

To evaluate the sources of variance in utilization of neuraxial anesthesia the investigators will use multilevel multivariable modeling strategies. This will allow identification of sources of variation (hospital, vs physician, vs patient characteristics), as well as identification of independent predictors of neuraxial use at each of these three levels. The investigators will also evaluate the independent association of hospital level variation in neuraxial use on our outcomes of interest using multilevel multivariable regression.

Interventions

PROCEDUREGeneral anesthesia

Sponsors

Ottawa Hospital Research Institute
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
66 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Had hip fracture surgery * Admitted to hospital on a non-elective basis

Exclusion criteria

* Do not hold a valid provincial health insurance account

Design outcomes

Primary

MeasureTime frame
Number of Participants With All-Cause Mortality at 30-daysDay of surgery to day of death, or up to 30 days, whichever comes first

Secondary

MeasureTime frame
Healthcare Costs From the Perspective of the Universal Healthcare System, Using Standardized Methods (Health System Performance Research Network 2013)Day of surgery to day of death, or 30 days after surgery, whichever comes first

Other

MeasureTime frame
Hospital Length of StayDay of surgery to day of discharge, or up to 365 days, whichever comes first

Countries

Canada

Participant flow

Participants by arm

ArmCount
Neuraxial Anesthesia
Participants in this group will be those who had a spinal or epidural anesthetic without concurrent general anesthesia Neuraxial anesthesia
57,080
General Anesthesia
Participants in this group will be those who had general anesthesia, including those who had a general plus a concurrent spinal or epidural anesthetic. General anesthesia
50,237
Total107,317

Baseline characteristics

CharacteristicNeuraxial AnesthesiaGeneral AnesthesiaTotal
Age, Continuous83 years
STANDARD_DEVIATION 7
82 years
STANDARD_DEVIATION 8
83 years
STANDARD_DEVIATION 8
Neighbourhood income quintile3 Neighbourhood income quintile3 Neighbourhood income quintile3 Neighbourhood income quintile
Sex: Female, Male
Female
41954 Participants36874 Participants78828 Participants
Sex: Female, Male
Male
15126 Participants13363 Participants28489 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
9,122 / 57,0800 / 0
other
Total, other adverse events
0 / 00 / 0
serious
Total, serious adverse events
0 / 00 / 0

Outcome results

Primary

Number of Participants With All-Cause Mortality at 30-days

Time frame: Day of surgery to day of death, or up to 30 days, whichever comes first

Population: Data were not collected from the participants in the General Anesthesia Arm/Group. Only neuraxial group data available for all cause 30-day mortality. The aim was to measure the association of hospital-level utilization of neuraxial anesthesia, independent of patient-level use, with 30-day survival and length of stay and costs.

ArmMeasureValue (COUNT_OF_PARTICIPANTS)
Neuraxial AnesthesiaNumber of Participants With All-Cause Mortality at 30-days9122 Participants
Secondary

Healthcare Costs From the Perspective of the Universal Healthcare System, Using Standardized Methods (Health System Performance Research Network 2013)

Time frame: Day of surgery to day of death, or 30 days after surgery, whichever comes first

Population: Data were not collected from the participants in the General Anesthesia Arm/Group. Only neuraxial group data available for healthcare costs. The aim was to measure the association of hospital-level utilization of neuraxial anesthesia, independent of patient-level use, with 30-day survival and length of stay and costs.

ArmMeasureValue (MEDIAN)
Neuraxial AnesthesiaHealthcare Costs From the Perspective of the Universal Healthcare System, Using Standardized Methods (Health System Performance Research Network 2013)22138 Canadian Dollars
Other Pre-specified

Hospital Length of Stay

Time frame: Day of surgery to day of discharge, or up to 365 days, whichever comes first

Population: Data were not collected from the participants in the General Anesthesia Arm/Group. Only neuraxial group data available for hospital length of stay The aim was to measure the association of hospital-level utilization of neuraxial anesthesia, independent of patient-level use, with 30-day survival and length of stay and costs.

ArmMeasureValue (MEDIAN)
Neuraxial AnesthesiaHospital Length of Stay9 Days

Source: ClinicalTrials.gov · Data processed: Feb 23, 2026