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No Need for Neuromuscular Blockade in Daycase Laparoscopic Surgery

No Need for Neuromuscular Blockade in Day Case Standardised Laparoscopic Surgery. A Consecutive Retrospective Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02782832
Enrollment
1245
Registered
2016-05-25
Start date
2016-05-31
Completion date
2016-08-31
Last updated
2018-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystitis, Inguinal Hernia, Direct, Umbilical Hernia

Keywords

Neuromuscular, Blockade, Surgery

Brief summary

This study analyse the need for neuromuscular blockade in consecutive routine laparoscopic procedures without standard use of neuromuscular blockade in an ambulatory laparoscopic surgery setting and analyse specific reasons for using neuromuscular blockade in individual patients. Furthermore, the study report the analgesic use in postoperative care unit and the discharge rate.

Detailed description

The study is retrospective, including consecutive patients in an unrestricted referral of patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair. Inclusion period was from 01.04.2013 to 31.03.2015. All patients received general anesthesia using propofol (2 mg/kg) and remifentanil (1 μg/kg/min) for induction. In patients where tracheal intubation was required, this was done without use of neuromuscular blocking drug; otherwise a proseal laryngeal mask was used. For the maintenance of anesthesia, additional continuous infusion of propofol (3-5 mg/kg/h) and remifentanil (0.3-0.5 μg/kg/min) was used. Data were derived from a prospective local database on demographics, anesthetic methods and supplements (i.e. need for neuromuscular blockade) and postoperative needs for supplementary analgesics besides the postoperative standard analgesic regimen, number of hours stayed in the ambulatory surgery department, and discharge rate (including reasons for hospital admittance).

Interventions

None listed

Sponsors

Hvidovre University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair

Exclusion criteria

* None

Design outcomes

Primary

MeasureTime frameDescription
Number of patients requiring neuromuscular blockadeAt time of surgeryData derived from a prospective local database on need for neuromuscular blockade in patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair.

Secondary

MeasureTime frameDescription
Analgesic use in postoperative care unitWithin 6 hours after surgeryAmount of opioids administered to the patients in the postoperative care unit
Hours stayed in the postoperative care unit1 to 6 hours after surgery
Maximum Visual analog score (VAS) for pain in the postoperative Care unit1 to 6 hours after surgery

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026