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Incidence and Risk Factor of Post-ERCP Pancreatitis in Chronic Pancreatitis

Changhai Hospital, the Second Military Medical University

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02781987
Enrollment
2028
Registered
2016-05-25
Start date
2011-01-31
Completion date
2015-05-31
Last updated
2017-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-ERCP Acute Pancreatitis

Brief summary

The purpose of this study is to compare the incidence of post-ERCP pancreatitis (PEP) in chronic pancreatitis (CP) patients to that in biliary disease patients, to determine whether CP patients in early clinical stage have a higher PEP incidence, and to identify the predictive and protective factors for PEP in chronic pancreatitis patients.

Detailed description

Analysis of patients with chronic pancreatitis (CP group) and biliary disease (BD group) in Changhai Hospital from January 2011 to May 2015 were conducted. Difference of PEP incidences between BD group and CP group, as well as between M-ANNHEIM subcategories were calculated by chi-square test or Fisher's exact test. The predictive and protective factors for PEP were investigated by univariate and multivariate analysis.

Interventions

OTHERchronic pancreatitis

patients with chronic pancreatitis

Sponsors

Changhai Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL

Eligibility

Sex/Gender
ALL
Age
5 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* patients with an endoscope inserted to cannulate the pancreatic/biliary duct were included.

Exclusion criteria

* patients in whom the papilla of Vater was not reached; * patients who underwent stent removal procedures without ductal cannulation; * patients in whom the intubation was failed.

Design outcomes

Primary

MeasureTime frame
Numbers of chronic pancreatitis patients with post-ERCP pancreatitis, diabetes mellitus, steatorrhea, previous pancreatitis, previous PEP, pancreatic divisum, jaundice, ESWL, pancreatic duct stone, drainage and minor papilla pancreatogram.8 months

Secondary

MeasureTime frame
Numbers of biliary disease patients with post-ERCP pancreatitis, previous pancreatitis and previous PEP.2 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 11, 2026