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Epidemiological and Molecular Colorectal Cancer Registry

Epidemiological and Molecular Colorectal Cancer Registry

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02781337
Acronym
EMR-CRC
Enrollment
2100
Registered
2016-05-24
Start date
2012-05-01
Completion date
2033-12-01
Last updated
2026-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer, Colorectal Neoplasms

Brief summary

This is a Registry that invites patients undergoing colorectal surgery for colorectal cancer. Epidemiological data is collected. The Registry includes tumor tissue and blood banks for analyzing different genetic mutations and disease-specific biomarkers.

Detailed description

This is a Registry that invites patients undergoing colorectal surgery for colorectal cancer. Epidemiological data is collected. The Registry includes tumor tissue and blood samples banks used to studied different genetic variants and disease-specific biomarkers present in patients with Lynch syndrome and others hereditary cancers. The aim of this registry is to set up the necessary resources to help basic and clinical research projects on colorectal cancer (CRC) within the Hospital Italiano de Buenos Aires (HIBA) and promote scientific collaborations between the HIBA and other institutions within and outside the country. To make this project, the following specific goals are proposed: Objective 1: Establishment of an efficient algorithm to enroll patients diagnosed with CRC from HIBA, through collaboration between the services of Surgery, Gastroenterology, Pathology, Oncology, Institute of Translational Medicine and Biomedical Engineering (IMTIB), Medical Clinic and Medical Informatics. Objective 2: Development of logistics for the connection and expansion of the bank of biological samples (DNA, serum) and tumor samples (tissue fixed in formalin, frozen tissue) to the CRC. Objective 3: Development of computer software to record data about patient enrolled in a dynamic way. Objective 4: Development of pipelines and create a supervisory committee to regulate the future of samples and data obtained through the registry, accord the current standards of ethical code, and improve the current collaborations with foreign researchers.

Interventions

None listed

Sponsors

Hospital Italiano de Buenos Aires
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
21 Years to 96 Years
Healthy volunteers
No

Inclusion criteria

* Adult patients undergoing colorectal surgery for colorectal cancer.

Exclusion criteria

* Unwillingness to participate.

Design outcomes

Primary

MeasureTime frameDescription
Overall survival5 yearsPatient overall survival at 5 years.
Disease-free survival5 yearsThe time free of disease recurrence will be estimated in the whole cohort and according to colorectal cancer stages and molecular profiles.

Secondary

MeasureTime frameDescription
Molecular characteristics of colorectal adenocarcinoma.0At initial diagnosis, molecular tumor markers will be determined in the tissue samples.

Countries

Argentina

Contacts

CONTACTCarlos Vaccaro, MD
carlos.vaccaro@hospitalitaliano.org.ar
CONTACTMaría L González, MD
marialaura.gonzalez@hospitalitaliano.org.ar
PRINCIPAL_INVESTIGATORCarlos Vaccaro, MD

Hospital Italiano de Buenos Aires

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 2, 2026