Cognitive-Motor Rehabilitation, Stimulant Drugs, and Active Control in the Treatment of ADHD

Comparison of the Effects of Cognitive-Motor Rehabilitation, Stimulant Drugs, and Active Control on Executive Functions and Clinical Symptoms of Attention Deficit/ Hyperactivity Disorder

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02780102

Acronym

ADHD

Enrollment

Registered

2016-05-23

Start date

2015-09-30

Completion date

2017-08-31

Last updated

2021-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention Deficit Hyperactivity Disorder

Keywords

ADHD, Cognitive-motor rehabilitation, Active Control Group, Stimulant Medication

Brief summary

The investigators administered a randomized controlled trial (RCT) through random assignment of children with ADHD into three different groups to compare the effects of cognitive-motor rehabilitation, immediate release methylphenidate, and an active control on the executive functioning, learning, and behavioral symptoms of children with ADHD.

Interventions

OTHERCognitive-Motor Rehabilitation

Cognitive-Motor Rehabilitation (CMR) group received 20 sixty-minute sessions of cognitive-motor exercises

DRUGRitalin

2 or 3 doses of 10 mg tablets of immediate-release Methylphenidate (Ritalin) per day for 8 week.

OTHERActive Control

Active Control group simultaneously received 20 sixty-minute sessions of low dose cognitive-motor exercises

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

MALE

Age

9 Years to 12 Years

Healthy volunteers

Inclusion criteria

* Receiving ADHD diagnosis * aged between 9 and 12 years * Intelligence Quotient (IQ)\>90

Exclusion criteria

* Severe co-morbid disorders, such as depression, op-positional defiant disorder and conduct disorder * A history of seizures during past 2 years * Disability or handicap preventing the child from participating cognitive-motor exercises * Sever medical conditions requiring immediate medical treatment

Design outcomes

Primary

Measure	Time frame
Forward/backward digit span tasks from the Wechsler intelligence scale for children 4th edition (WISC-IV)	12 months
Span board task from the Lumosity.com online brain training software	12 months
Listening span task (L.SPAN)	12 months
Stroop color-word test	12 months
Tower of London test (TOL)	12 months
Restricted academic situation scale (RASS)	12 months
Arithmetic task from WISC-IV testing battery	12 months
Swanson, Nolan, and Pelham's parent rating scale (SNAP-IV)	12 months
Dictation and Spelling examination	12 months

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026