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High Flow Oxygen With THRIVE Gives Better Oxygenation in Rapid Sequence Induction Patients

High Flow Oxygen With THRIVE Gives Better Oxygenation in Rapid Sequence Induction Patients

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02777840
Acronym
THRIVE/RSI 1
Enrollment
80
Registered
2016-05-19
Start date
2015-03-31
Completion date
2018-03-31
Last updated
2017-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High Flow Oxygen in Rapid Sequence Induction, Airway Morbidity

Brief summary

High flow oxygen results in better oxygenation in emergency cases needing rapid sequence induction for anaesthesia. Secondary outcome measure is time for any desaturation.

Detailed description

The investigators intend to do the study using high flow oxygen for all emergency cases needing rapid sequence induction. As part of the study the Investigators will measure the oxygen levels in the blood gas sample of the patient and the heart rate of anesthetist in charge of the airway management. After the airway is secured the time for desaturation will be noted.

Interventions

DEVICEface mask oxygen

oxygen given by face mask as per routine practice

High flow oxygen given via optiflo machine / device

Sponsors

St George's, University of London
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Emergency patients needing rapid sequence induction for surgery * ≥ 16 years * Able to give consent

Exclusion criteria

* Patients age under 16 years * Inability to give consent * Severe respiratory disease

Design outcomes

Primary

MeasureTime frameDescription
Oxygen levels in blood gas sampleintraoperativeOxygen levels in blood gas sample after the airway is secured

Secondary

MeasureTime frameDescription
time to desaturationintraoperative or 10 minutes after intubationafter airway is secured time will be noted for oxygen levels to fall to 92% before the ventilation is started.
heart rate of anaesthetist performing the intubationDuring the process of induction of anaesthesia and intubation upto 5 minutes post intubation

Countries

United Kingdom

Contacts

Primary ContactLucy Parker
lparker@sgul.ac.uk0208 266 6397

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026