Tumor Monitoring Using Thermography During Radiation Therapy

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02776995

Enrollment

Registered

2016-05-19

Start date

2014-11-30

Completion date

2020-12-30

Last updated

2019-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malignancy

Brief summary

This research aims to investigate the correlation between tumor temperature difference and biological factors, such as size, metabolism, treatment response, and tumor aggressiveness. In addition, normal tissue response to adjuvant radiation therapy in treated organs following surgery, will be evaluated.

Detailed description

During radiation session, the investigators would evaluate the changes that will be detected by thermal imaging and correlate them with visible side effects as well as with known tumor biology factors and skin-tumor distance.

Interventions

OTHERThermography imaging

Thermography imaging of the treated - irradiated body area.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* signed informed consent * will undergo radiation therapy for palliation or curative intent due to cancer, biopsy proven

Exclusion criteria

* not eligible to sign informed consent

Design outcomes

Primary

Measure	Time frame	Description
Measurement of IR : Infra-Red radiation emitted at wavelengths 0.8-1nm	Before the first fraction of radiation and every 5 fraction until the end of radiation therapy, approximately 4-5 weeks.	Mathematical analysis of the thermic image

Secondary

Measure	Time frame	Description
Dermal side effects during radiation therapy using CTCAE v4.0	Before the first fraction of radiation and every 5 fraction until the end of radiation therapy, approximately 4-5 weeks.	Clinical assesment of the side effects by physician.
US/CT scans	The tumor size in cubic cm will be mesured prior to first fraction of radiation, and 2 weeks following the end of radiation session. Time for final evaluation: approximately 6-7 weeks.	The tumor size will be measures to evaluate the efficacy of the radiation treatment.

Countries

Israel

Contacts

Primary ContactMerav Ben-David, MD

merav.ben-david@sheba.health.gov.il972-3-5305086

Backup ContactZvi Symon, MD

zvi.symon@sheba.health.gov.il972-3-5305080

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026