Hirschsprung Disease
Conditions
Keywords
enhanced recovery after surgery, hirschsprung disease
Brief summary
The study is designed to determine if enhanced recovery after surgery (ERAS) principles could provide benefit for pediatric patients undergoing radical surgery for Hirschsprung's Disease (HD). Half of patients will receive the ERAS program, while the other half will receive the traditional program.
Detailed description
Optimized peri-operative care within an enhanced recovery after surgery (ERAS) protocol is designed to reduce morbidity after surgery, resulting in a shorter hospital stay. The present study evaluated this approach in the context of radical surgery for pediatric patients with Hirschsprung's Disease(HD). Patients undergoing radical surgery for HD will be enrolled in a randomized clinical trial comparing ERAS protocol vs a control group that received standard care. The primary outcome is median length of postoperative hospital stay. The second outcomes include postoperative complications rates，gastrointestinal function recovery time，mean cost per patient，readmission rates within postoperative 30 days，and the levels of stress and inflammation marker.
Interventions
optimized peri-operative protocol
PROCEDURETraditional Program
traditional standard protocol
Sponsors
Xuzhou Medical University
Soochow University
Wuxi People's Hospital
Weibing Tang
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 14 Years
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of Hirschsprung Disease
Exclusion criteria
* with other disease * receive emergency surgery * need to do the ostomy * full colonic Hirschsprung Disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| median length of postoperative hospital day | 30days |
Secondary
| Measure | Time frame |
|---|---|
| postoperative complications rates | within 30 days |
| gastrointestinal functional recovery time | within 30 days |
| mean cost per patient | within 30 days |
| the readmission rates | within 30 days |
| the level of stress and inflammation marker | within 30 days |
Countries
China
Contacts
Primary ContactWeibing Tang, MD&PhD
Outcome results
None listed