PRP Gel in Wound Closure in Recurrent CS

Platelet Rich Plasma Gel in Wound Closure in Recurrent Cesarean Section:Randomized Controlled Trial

Status

Completed

Phases

Phase 1Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02775747

Acronym

PRP-CS

Enrollment

128

Registered

2016-05-18

Start date

2016-04-30

Completion date

2017-04-30

Last updated

2017-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Previous Incision, Scar; Previous Cesarean Section

Brief summary

There is limited application of the use of PRP in obstetrics, therefore there is a need for assessment if it is efficacy in improving skin wound healing in cesarean section.

Detailed description

This study aims to assess the efficacy of injection of platelet rich plasma into the wound of recurrent cesarean section for improving wound healing and enhancing the shape of the wound in women undergoing cesarean section.

Interventions

BIOLOGICALplatelet rich plasma gel

Platelet rich plasma is prepared from fresh whole blood which is collected from a peripheral vein stored in acid citrare dextrose solution A (ACD-A)anticoagulant and processed to increase platelets by separating various components of blood

BIOLOGICALsaline

64 controlled women with recurrent cesarean section and fullfit to all inclusion and exclusion craiteria will reseve saline injection at time of wound closure

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

25 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* elective cesarean section * Body mass index 18:25 * Hemoglobin more than 10.5 g/d * Albumin within normal more than or equal 3.5 g/d

Exclusion criteria

* medical disorders(Diabetes mellitus,heart disease,hypertension,systemic lupus erythematosus) * high risk pregnancy as (placenta previa,placenta accreta) * patient on corticosteroids medication * primigravida subjected cesarean section * complicated cesarean section (increased operation time,blood transfusion, drain, scrubbing of multiple surgeons) * cesarean section due to chorioaminionitis * postoperative complication such as:postpartum hemorrhage, paralytic ileus, sever distention..) will be dropped out from the study

Design outcomes

Primary

Measure	Time frame	Description
Efficacy of PRP in Wound healing in cesarean section by 100 mm visual analog scale	one month	Efficacy of PRP in Wound healing in cesarean section by 100 mm visual analog scale (VAS) for wound healing

Secondary

Measure	Time frame	Description
Assessment of the Cosmetic results of the wound by Modified Vancouver scar scale	one month	Assessment of the Cosmetic results of the wound by Modified Vancouver scar scale

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026