Cochleural Alternating Acoustic Beam Therapy (CAABT) Versus Masking Intervention for Tinnitus

Cochleural Alternating Acoustic Beam Therapy Versus Masking Intervention for Tinnitus: A Randomised Controlled Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02774122

Enrollment

Registered

2016-05-17

Start date

2016-04-30

Completion date

2018-10-31

Last updated

2018-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tinnitus, Subjective

Brief summary

This study is to compare the effectiveness of CAABT and masking therapy in the management of subjective tinnitus in adults.Half of participants will receive CAABT, while the other half will receive masking therapy.

Detailed description

Masking intervention was a standard monophone tinnitus masking therapy. It was usually a narrow-band noise matched with tinnitus frequency (Tf). CAABT was an innovative tinnitus intervention which based on neural science and cochlear plastic research and aimed to reprogram the central auditory system to neutralize the discordant responses of the dysfunctioning cochlea via acoustic beaming stimuli.

Interventions

DEVICECAABT

CAABT was an innovative tinnitus intervention which based on neural science and cochlear plastic research and aimed to reprogram the central auditory system to neutralize the discordant responses of the dysfunctioning cochlea via acoustic beaming stimuli.

DEVICEmasking therapy

Masking intervention was a standard monophone tinnitus masking therapy.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Unilateral tinnitus * Ages between 18-80 years * Tinnitus undergone for more than 6 months * Hearing loss of the tinnitus ear not affect communication * The main tinnitus frequency is less than 8 KHz * Primary tinnitus

Exclusion criteria

* Secondary tinnitus * Hyperacusis * Patients were accepting any therapy about tinnitus * Those who have serious mental illness * Patients who can't fit the audiological examination and tinnitus tests * Most of the hearing loss in the middle and severe hearing loss of the tinnitus ear * Any MRI contraindications

Design outcomes

Primary

Measure	Time frame
Change from Baseline in Tinnitus Subjective Measures at 12 weeks: pure tone audiometry	baseline and 12 weeks
Change from Baseline in Tinnitus Subjective Measures at 12 weeks: tinnitus loudness	baseline and 12 weeks
Change from Baseline in Tinnitus Subjective Measures at 12 weeks: minimize masking level	baseline and 12 weeks
Change from Baseline in Tinnitus Subjective Measures at 12 weeks: the Chinese version of Tinnitus Handicap Inventory scale	baseline and 12 weeks
Change from Baseline in Tinnitus Subjective Measures at 12 weeks: the Visual Analog Scale	baseline and 12 weeks

Secondary

Measure	Time frame
Change from Baseline in Tinnitus Objective Measure at 12 weeks: functional magnetic resonance imaging (fMRI)	baseline and 12 weeks

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 7, 2026