Characteristics of Rheumatoid Arthritis Patients With Atlantoaxial Synovitis Detected by Plain X-ray and MRI

Characteristics of Rheumatoid Arthritis Patients With Asymptomatic Versus Symptomatic Atlantoaxial Joint Affection Detected by Plain X-ray and Magnetic Resonance Imaging

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02774070

Acronym

MRI

Enrollment

Registered

2016-05-17

Start date

2016-10-31

Completion date

2017-02-28

Last updated

2020-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neck Pain

Keywords

AAJ RA MRI synovitis

Brief summary

This study detects the presence of atlantoaxial joint affection in symptomatic versus asymptomatic rheumatoid arthritis patients revealed by plain X-ray and magnetic resonance imaging of the cervical spine

Detailed description

Atlantoaxial joint affection in rheumatoid arthritis patients may have life-threatening complications if not detected early. It may not be detected unless it becomes symptomatic. However, asymptomatic atlantoaxial joint affection is not uncommon. Investigators will try to detect atlantoaxial joint affection at an early stage and its relation to symptomatology and other disease criteria. So investigators will use conventional plain X-ray examination combined with magnetic resonance imaging of the cervical spine to detect soft tissue as well as bony changes of this condition.

Interventions

RADIATIONPlain X-ray

antero-posterior, lateral neutral, flexion, extension and open-mouth views

RADIATIONMagnetic resonance imaging

Magnetic resonance imaging sagittal T1W,T2W and STIR, axial T1W and coronal T2W and post contrast sagittal and axial sequences

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Rheumatoid arthritis patients complaining or not complaining of atlantoaxial affection symptomatology

Exclusion criteria

* Pregnant females * Patients with pacemakers or metallic bony plates. * Patients that have claustrophobia

Design outcomes

Primary

Measure	Time frame	Description
Prevelance of atlantoaxial joint affection in clinically and laboratory proven rheumatoid arthritis patients	3 months	Prevelance of atlantoaxial joint affection in symptomatic versus asymptomatic rheumatoid arthritis patients

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026