Asthma
Conditions
Brief summary
Eviction methods for dust mite allergy have been evaluated in asthma control in a recent Cochrane meta-analysis. None have shown efficacy on asthma control and there are not recommended. The purpose is to evaluate the efficacy of a new commercialized system (Acar'Up) to decrease dust mite load and to assess its impact on the possibility to perform inhaled corticosteroids step down in stable asthmatics.
Detailed description
Eviction methods for dust mite allergy have been evaluated in asthma control in a recent Cochrane meta-analysis. None have shown efficacy on asthma control and there are not recommended. The purpose is to evaluate the efficacy of a new commercialized system, Acar'Up (a spray pulverized on a technical textile that traps the dust mite) to decrease dust mite load and to assess its impact on the possibility to perform inhaled corticosteroids step down in stable asthmatics.
Interventions
DEVICEAcar'up system
DEVICEAcar'up placebo system
Sponsors
Centre Hospitalier Universitaire Saint Pierre
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
16 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* confirmed asthma diagnosis * controlled asthma for more than 3 months * treatment with inhaled corticosteroids * dust mite allergy proved by skin tests ou specific immunoglobulin E
Exclusion criteria
* chronic obstructive pulmonary disease, bronchiectasis, Fibrosis, tuberculosis * asthma-chronic obstructive pulmonary disease overlap syndrome * ongoing desensitization for dust mite * pregnancy * previous use of Acar'up
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| assessment of successful stepdown of inhaled corticosteroid using clinical evaluation | 4 months | assessment of the successful step down of inhaled corticosteroid using clinical evaluation |
| assessment of successful stepdown of inhaled corticosteroid using asthma scale: asthma control questionnaire (ACQ) | 4 months | assessment of the successful step down of inhaled corticosteroid using asthma scale: asthma control questionnaire (ACQ) |
| assessment of successful stepdown of inhaled corticosteroid using asthma quality of life questionnaire (AQLQ) | 4 months | assessment of the successful step down of inhaled corticosteroid using asthma quality of life questionnaire (AQLQ) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| assessment of asthma control by the asthma control questionnaire questionnaire | 4 months | by the asthma control questionnaire |
| assessment of asthma quality of life by the asthma quality of life questionnaire | 4 months | by the asthma quality of life questionnaire |
| assessment of rhinitis control by the rhinitis quality of life questionnaire | 4 months | by the rhinitis quality of life questionnaire |
Countries
Belgium
Outcome results
None listed