Asthma
Conditions
Brief summary
The aim of this project is to estimate the quality of life for people with asthma and specifically the loss in quality of life associated with an asthma-related crisis event (accident and emergency (A&E) attendance or admission).
Detailed description
Asthma is a serious respiratory condition which causes shortness of breath, chest tightness and wheezing. Quality of life can have an impact on asthmatics due to such symptoms. Previous studies capture quality of life at specific time points (e.g. baseline, 1 month, 3 months), and the assumption of a steady improvement is made. However, these assumptions and time points could miss an asthma event in between. Therefore, the investigators aim to provide a more accurate estimation of the loss in quality of life by following participants over an 8 week period from when the participants have attended A&E or been admitted to hospital following an asthma attack. This will be done by using different quality of life methods, and analysed by calculating the difference between the quality of life scores from A&E attendance / hospital admission and follow-ups.
Interventions
None listed
Sponsors
National Institute for Health Research, United Kingdom
University of East Anglia
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Male or Female 18 years old and over * Has asthma alone, or asthma with Chronic Obstructive Pulmonary Disease (COPD) or asthma with a respiratory infection * Speaks English * Not in need of help from carer / guardian to complete questionnaires * Not hypoxemic * Not participated in the study before * Able to give informed consent
Exclusion criteria
* Younger than 18 years old * Does not speak English * Has participated in the study before * Remains hypoxemic despite oxygen therapy * Impaired capacity to consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| EuroQol 5 Dimensions 5 Level (EQ-5D-5L) | Once a week from baseline until week 8 | A generic quality of life questionnaire |
| Asthma Quality of Life Questionnaire (AQLQ) | Once a month from baseline to week 8 | A disease-specific quality of life questionnaire |
| Peak flow and asthma symptom diary | Every day from baseline to week 8 | Assessment of peak expiratory flow and asthma symptoms |
| Time Trade-Off | Once a month from baseline to week 8 | Assessment of quality of life. Completed at Norfolk and Norwich University Hospital only. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Productivity Questionnaire | Week 4 | Assessment of time lost from work, study or activities from having an asthma exacerbation |
Countries
United Kingdom
Outcome results
None listed