The Utility of Pulse Pressure Variation to Predict the Fluid Responsiveness During Pneumoperitoneum and Reverse-Trendelenburg Position

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02771067

Enrollment

Registered

2016-05-12

Start date

2016-09-29

Completion date

2017-02-23

Last updated

2017-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General Anesthesia

Brief summary

The purpose of this study is to investigate the validity of pulse pressure variation to predict fluid responsiveness in patients undergoing robotic or laparoscopic gastrectomy.

Interventions

PROCEDUREFluid infusion

Fluid infusion will be performed using 6% hydroxyethyl starch. Pulse pressure variation and stroke volume will be measured before and after fluid infusion.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Inclusion criteria

* adult patients aged over 19 years who are scheduled for robotic or laparoscopic gastrectomy

Exclusion criteria

* cardiac arrhythmia * valvular heart disease * ischemic heart disease * left ventricular ejection fraction less than 40% * Pulmonary disease * esophageal disease * upper gastrointestinal bleeding * Body mass index more than 40 kg/m2.

Design outcomes

Primary

Measure	Time frame	Description
Pulse pressure variation	During the surgery. At Day 0.	Ability of pulse pressure variation to predict fluid responsiveness will be evaluated.

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026