the Effect of Spray on Propofol Injection Pain

the Effect of Ethyl Chloride Spray on Propofol Injection Pain

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02770690

Enrollment

Registered

2016-05-12

Start date

2016-04-30

Completion date

2016-11-30

Last updated

2016-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Brief summary

While propofol is widely used an anesthetic induction medication, it causes the mild to moderate pain. Investigators will investigate the effect of ethyl chloride spray on propofol injection pain.

Interventions

DRUGethyl chloride spray

apply the spray for 5 seconds on the dorsal hand before propofol iv injection

DRUGlidocaine

apply lidocaine under the tourniquet state before propofol iv injection

DRUGplacebo

apply normal saline before propofol iv injection

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 65 Years

Healthy volunteers

Inclusion criteria

* the female patients undergoing hysteroscopy

Exclusion criteria

* the patients who are pregnant, have Raynaud's syndrome, or receive the pain killer

Design outcomes

Primary

Measure	Time frame	Description
propofol injection pain	right after the propofol injection	Propofol injection pain will be measured using the VAS (Visual analogue scale; 0cm=no pain, 10cm=the worst pain)

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026