The National Center for Testing Treatments in Chronic Spinal Cord and Traumatic Brain Injury

Status

Enrolling by invitation

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02769416

Acronym

NCTT

Enrollment

5000

Registered

2016-05-11

Start date

2015-12-01

Completion date

2035-12-01

Last updated

2026-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Cord Injury, Traumatic Brain Injury

Keywords

spinal cord injury, traumatic brain injury

Brief summary

The NCTT is a prospective, multicenter, observational research network for subjects with chronic spinal cord and/or chronic traumatic brain injury.

Detailed description

Current treatment for Spinal Cord Injury and Traumatic Brain Injury focuses on stabilizing the patient and preventing secondary injury with the aim of maximizing the best chance of recovery. Most patients will show varying amounts of recovery, but, when the injury is severe, that recovery is only partial. Enrollment in the NCTT will allow for classification and characterization of injury, function, co-morbidities, secondary issues/problems, research interests and will serve as a conduit for enrollment into interventional studies.

Interventions

OTHERData and sample repository

Subjects with spinal cord and/or traumatic brain injury, family members and healthy volunteers will provide data and samples.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* History of spinal cord injury and/or brain injury * Able to provide HIPAA authorization to share prior medical records/imaging * Age 18 and older.

Exclusion criteria

* Life expectancy less than 6 months, vegetative state or co-existing disease or other characteristic that precludes appropriate diagnosis of spinal cord or brain injury. * Other condition that, in the opinion of the site investigator, would interfere with adherence to study requirements. * Inability or unwillingness of subject or legal guardian/representative to give informed consent (e.g., ward of the state).

Design outcomes

Primary

Measure	Time frame	Description
International Standard Neurological Classification of Spinal Cord Injury	greater than 6 months post-injury	functional ability (sensory and motor) for spinal cord injury subjects
Disability Rating Scale	greater than 6 months post-injury	functional outcome scale for brain injury subjects

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORGeorgene Hergenroeder, PhD

UTHealth

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 17, 2026