Effects of Early Sensory Reeducation Programs Using Mirror Therapy for Patients With Peripheral Nerve Injuries

A Touch-Observation and Task-based Mirror Therapy Protocol (MTPTOT) to Improve Sensorimotor Control and Functional Capability of Hands for Patients With Peripheral Nerve Injury

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02768857

Enrollment

Registered

2016-05-11

Start date

2014-12-31

Completion date

2015-10-31

Last updated

2016-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Motor Deficit, Rehabilitation, Sensation Disorders

Brief summary

This study evaluated the effects of an integrated program of touch-observation and task-based mirror therapy on sensorimotor function in nerve injury patients. Before the return of protective sense (Value of Semmes-Weinstein monofilament test \> 4.31), half of the participants received 15 minutes of mirror therapy program, followed by 20 minutes of regular hand therapy and 20 minutes of physiotherapy.While the other half received 15 minutes protective sensory reeducation programs, 20 minutes of regular hand therapy and 20 minutes of physiotherapy in each treatment session. Once the patients had regained the protective sense (Value of Semmes-Weinstein monofilament test \< 4.31), the discriminative sensory reeducation program was started for the participants in both groups. The hypothesis was that using the mirror therapy for sensorimotor reeducation in the early phase after nerve repair would yield better results with regard to the returning of sensation, sensorimotor control ability and hand function than using a classical reeducation program alone.

Interventions

BEHAVIORALSensorimotor reeducation programs

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* median or ulnar nerve injury, * a combination of nerve and tendon or vascular injury, * injury sites between the level of mid-palm and elbow, and * the protective sensation of the hand is lacking or impaired.

Exclusion criteria

* patients with deficits in cognition or language comprehension, as well as severe limitations in the range of motion of the upper limbs.

Design outcomes

Primary

Measure	Time frame
Change from baseline result of Semmes-Weinstein monofilament (SWM) test at 12 weeks and 24 weeks	baseline, 12 weeks and 24 weeks
Change from baseline result of Purdue pegboard test at 12 weeks and 24 weeks	baseline, 12 weeks and 24 weeks
Change from baseline result of Minnesota manual dexterity test at 12 weeks and 24 weeks	baseline, 12 weeks and 24 weeks
Change from baseline result of Pinch-holding-up-activity (PHUA) test at 12 weeks and 24 weeks	baseline, 12 weeks and 24 weeks

Secondary

Measure	Time frame
Change from baseline result of Static two-point discrimination (S2PD) test at 12 weeks and 24 weeks	baseline, 12 weeks and 24 weeks

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026