the Effect of Gut Microbiota on the Prognosis of Sepsis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02768324

Enrollment

Registered

2016-05-11

Start date

2017-05-01

Completion date

2019-09-01

Last updated

2017-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Keywords

sepsis, Gastrointestinal Microbiome, Gut microbiota, Gut Flora, Intestinal Flora

Brief summary

Sepsis is a life-threatening condition that arises when the body's response to infection injures its own tissues and organs. Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. Clinically, sepsis patients with diarrhea often result in a bad prognosis. Gut microbiota consists of a complex community of microorganisms that live in the digestive tracts of animals. The gut microbiota comprises the largest and most diverse reservoir of mutualistic microorganisms associated with animals. The aims of this study is to determin the effect of gut microbiota on the prognosis of Sepsis, by using 16s pyrosequencing, comparing the blood culture result.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Subjects diagnosed with sepsis * 18 years to 65 years of age

Exclusion criteria

* patients had complications such as acute cerebral infarction or acute myocardial infarction * The use of antibiotics, pro-prebiotics within 3 months * \<18 years or \>65 years * History of intestinal surgery * patients withdraw from this study

Design outcomes

Primary

Measure	Time frame
Discharged from ICU	7 days

Contacts

Primary ContactLi Deng, PhD

0086-18819351723

Outcome results