Ticagrelor in Fuwai Hospital

TIFU: A Non-Interventional, Descriptive Cohort Study to Describe the Use of Ticagrelor in Patients With Acute Coronary Syndrome (TIFU: Ticagrelor in Fuwai Hospital)

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02765711

Acronym

TIFU

Enrollment

1200

Registered

2016-05-09

Start date

2016-05-31

Completion date

2018-05-31

Last updated

2016-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome

Keywords

ticagrelor, acute coronary syndrome

Brief summary

This is a single-arm non-interventional cohort study. This study is to describe the contemporary use of ticagrelor in a real-world setting, to reflect its acceptance and patients' compliance, and to observe its one-year safety in patients with acute coronary syndrome in Fuwai Hospital.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. ≧18 years 2. Established diagnosis of acute coronary syndrome 3. The use of ticagrelor in hospital 4. agree to join this clinical trial and sign informed consent

Exclusion criteria

1. Life-expectancy \<1 year 2. Dialysis required

Design outcomes

Primary

Measure	Time frame
Number of participants with switching between clopidogrel and ticagrelor	12 months
Number of participants with switching between clopidogrel and ticagrelor without a reloading dose	12 months
Number of Participants with discontinuation of P2Y12 receptor antagonist	12 months
Number of Participants with ticagrelor combined with other anticoagulants	12 months

Secondary

Measure	Time frame	Description
Cardiovascular Mortality, Myocardial Infarction(MI), Ischemic Stoke	12 months	composite incidence Myocardial infarction is defined and subclassified in accordance with ACC/AHA/ESC third universal definition of myocardial infarction Ischemic stroke: an acute episode of focal cerebral, spinal, or retinal dysfunction caused by infarction, defined by at least one of the following: 1. Pathological, imaging, or other objective evidence of acute, focal cerebral, spinal, or retinal ischemic injury in a defined vascular distribution 2. Symptoms of acute cerebral, spinal, or retinal ischemic injury persisting ≧24 h, with other etiologies excluded Hemorrhage may be a consequence of ischemic stroke. In this situation, the stroke is an ischemic stroke with hemorrhagic transformation and not a hemorrhagic stroke.
Number of bleeding event will be recorded (defined in accordance with PLATO definition)	12 months	—

Countries

China

Contacts

Primary ContactHongbing Yan, MD

yanhongbingsuifang@163.com+8610-88322287

Backup ContactJuan Liu, MD

tifuliu@163.com+8610-88322287

Outcome results