An Interocular Comparative Study of Unilateral Cataract

Interocular Anatomical and Visual Functional Differences in Pediatric Patients With Unilateral Cataracts at 3 Months Post-surgery: A Cross-sectional Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02765230

Enrollment

Registered

2016-05-06

Start date

2014-01-31

Completion date

2016-01-31

Last updated

2016-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract

Brief summary

The purpose of this cross-sectional study is to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to explore any possible interocular differences and their possible relationships.

Detailed description

Great advances have been made in managing pediatric cataracts during the last several decades; these advances have contributed to a decrease in the incidence of postoperative complications and improvement in visual outcomes.Early cataract removal and replacement with an intraocular lens (IOL) represent the most appropriate treatments to avoid irreversible amblyopia.Although screening and timely surgical intervention play a key role in improved best corrected visual acuity (BCVA) among pediatric patients with cataracts, determining the prognosis for an individual remains difficult, particularly for unilateral cataract. Few studies have focused on the interocular differences in ocular anatomic parameters other than axial length in unilateral pediatric cataract after surgery, the significance of which for the possible interocular visual functional difference remains unclear. Therefore, the investigators conducted this cross-sectional study to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to explore any possible interocular differences and their possible relationships.

Interventions

None listed

Study design

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

No minimum to 10 Years

Healthy volunteers

Inclusion criteria

* Children with uncomplicated surgeries * Children who were younger than 10 years old * Children with unilateral total cataract

Exclusion criteria

* Premature birth * Microphthalmia * Micro-or Megalocornea * Keratoconus * Glaucoma * Traumatic or complicated cataracts * Vitreous and retinal diseases * Any previous surgeries

Design outcomes

Primary

Measure	Time frame	Description
Interocular anatomical parameters in pediatric unilateral cataract patients measured by pentacam	Baseline	The Parameters are measured by pentacam (Oculus Inc., Wetzlar, Germany), a rotating Scheimpflug camera.
Visual function in pediatric unilateral cataract patients measured by Teller Acuity Cards	Baseline	The visual function is measured by Teller Acuity Cards (Stereo Optical Company, Inc., IL, USA).

Countries

China

Outcome results