Comparison of Skin Prick Testing Results of Local and Imported Pollen Allergen Extracts and Specific IgE

Comparison of Skin Prick Testing Results of Local and Imported Pollen Allergen Extracts (Bermuda ,Johnson Grasses and Careless Weed) With Specific IgE Levels.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02764827

Enrollment

Registered

2016-05-06

Start date

2014-11-30

Completion date

2016-04-30

Last updated

2016-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Immediate Type Hypersensitivity

Keywords

skin prick test, grass and weed pollens

Brief summary

Pollen allergen extracts are prepared locally and checked for efficacy by comparison to imported allergens and specific IgE.

Detailed description

Skin prick test (SPT) and specific IgE (sIgE) are approved for evaluation of allergen sensitization. Local allergen extracts are cheaper and more available but need standardization. Pollen allergen extracts: Bermuda, Johnson and careless weed are locally prepared and compared mean wheal diameter of skin prick test to imported allergens and also to specific IgE.

Interventions

BIOLOGICALPollen sensitization

Skin prick test with local and imported Bermuda, Johnson and careless weed allergen extracts at concentration of 10,000, 3,000, 1,000 and 300 AU/mL and measure specific IgE levels

Study design

Observational model

CASE_CROSSOVER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Positive skin prick test to Bermuda or Johnson or careless weed

Exclusion criteria

* Chronic diseases such as heart disease, liver, renal and severe sepsis * Severe allergic symptoms such as anaphylaxis * Extensive skin rashes * Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Mean wheal diameter of local and imported grass and weed pollens	18 months	compare mean wheal diameter of skin prick test of different concentration among local, imported allergen extract and specific IgE levels of Bermuda grass, Johnson grass and careless weed
sIgE levels of Bermuda grass,Johnson grass and careless weed	18 months	Measure level of sIgE of Bermuda grass,Johnson grass and careless weed and compare to SPT results

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026