General Anesthesia
Conditions
Brief summary
The purpose of this study is to investigate and compare the postoperative quality of recovery between the deep neuromuscular blockade and moderate neuromuscular blockade during robotic gastrectomy.
Interventions
neuromuscular blockade will be performed using a continuous infusion of rocuronium. Post-tetanic count 1-2 will be maintained during surgery. After the end of surgery, sugammadex of 4 mg/kg will be administered to reverse neuromuscular blockade.
neuromuscular blockade will be performed using a continuous infusion of rocuronium. Train-of-four 1-2 will be maintained during surgery. After the end of surgery, sugammadex of 2 mg/kg will be administered to reverse neuromuscular blockade.
Sponsors
Yonsei University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
19 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* adult patients aged 19-80 years who are scheduled for robotic gastrectomy
Exclusion criteria
* Neuromuscular disease * History of malignant hyperthermia * Significant renal or hepatic dysfunction * Allergy to sugammadex or rocuronium
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative quality of recovery | within 48 hours after the end of surgery. | The postoperative quality of recovery will be evaluated at 24 and 48 hours after the end of surgery by the investigator who are blinded to the group assignments. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Surgical condition | within 48 hours after the end of surgery | Surgical condition will be evaluated after the end of surgery by the investigator who are blinded to the group assignments. |
| shoulder pain | within 48 hours after the end of surgery | shoulder pain will be evaluated after the end of surgery by the investigator who are blinded to the group assignments. |
| abdominal pain | within 48 hours after the end of surgery | abdominal pain will be evaluated after the end of surgery by the investigator who are blinded to the group assignments. |
| nausea and vomiting | within 48 hours after the end of surgery | nausea and vomiting will be evaluated after the end of surgery by the investigator who are blinded to the group assignments. |
Countries
South Korea
Outcome results
None listed