Cataract
Conditions
Brief summary
The purpose of prospective cohort study is to describe the developmental profile of refraction change in a large cohort of Chinese CC patients. The decisive factors to the range of myopic shift in unilateral CC appeared to be different from that in bilateral CC, indicating dramatic differences in the etiopathogenesis and refractive prognosis between bilateral and unilateral CC.
Detailed description
The refractive status is crucial to visual function and may change throughout life. For patients with congenital cataract (CC), the developmental profile of refraction is complicated due to the potential influences of diverse clinical manifestations and various treatments, and has not yet been fully characterized. The investigator described the developmental profile of refraction change in a large cohort of Chinese CC patients. The decisive factors to the range of myopic shift in unilateral CC appeared to be different from that in bilateral CC, indicating dramatic differences in the etiopathogenesis and refractive prognosis between bilateral and unilateral CC. The refraction data from CC patients provided in the study are of clinical significance to the guidelines for CC treatment, especially for IOL calculation concerning the laterality of CC.
Interventions
None listed
Sponsors
Ministry of Health, China
Sun Yat-sen University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Children with uncomplicated surgeries * Children with unilateral/bilateral cataract
Exclusion criteria
* Corneal diseases * Lens luxation * Glaucoma * Retinal diseases * Nystagmus and nanophthalmos
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The refraction status (presented as spherical equivalent, SE) | Baseline | Refractions were conducted with objective retinoscopy and cycloplegia, and performed by experienced optometrists. |
Countries
China
Outcome results
None listed