Expression of HOXA10 and HOXA11 in the Endometrium of Infertility Patients With an Endometrial Polyp Before and After Polypectomy

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02761278

Enrollment

Registered

2016-05-04

Start date

2016-07-31

Completion date

2017-07-31

Last updated

2016-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

The aim of this study is to measure the expression of HOXA10 and HOXA11 in the endometrium of infertility patients with an endometrial polyp before and after polypectomy. HOXA10 and HOXA11 are well-established markers of implantation. It is uncertain as to whether an endometrial polyp interferes with embryo implantation. A higher expression of HOXA10 and HOXA11 after polypectomy can indicate that endometrial polyp does interfere with embryo implantation.

Interventions

PROCEDUREEndometrial biopsy

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 40 Years

Healthy volunteers

Inclusion criteria

* Infertile women with endometrial polyp

Exclusion criteria

* Endometriosis * Polycystic ovary syndrome * Hydrosalpinx * Sub-mucus myoma * Women who have taken hormonal therapy in the preceding month

Design outcomes

Primary

Measure	Time frame
Comparison of amounts of HOXA10 and HOXA11 expressed before and after polypectomy	Four months

Contacts

Primary ContactGuy Shrem, MD

dr.shremguy@gmail.com

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026