Perioperative Heart Rate Variability Analysis in Realtime

Perioperative Heart Rate Variability Analysis in Realtime: Detection of Cardiovascular and Autonomic Dysfunction

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02761031

Acronym

PHERVR

Enrollment

Registered

2016-05-04

Start date

2016-04-30

Completion date

2018-08-31

Last updated

2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Rate and Rhythm Disorders, Individuality, Perioperative/Postoperative Complications, Surgical Complications From General Anesthesia

Keywords

Heart rate variability, Electrocardiography, Observational study, Non-interventional study, Risk assessment, Perioperative

Brief summary

This study will record patient electrocardiograms - as well as various other body signals (e.g., blood pressure, pulse wave, peripheral hemoglobin oxygen saturation) - as monitored routinely both during and immediately subsequent to surgical operations performed under general anesthesia. Through retrospective analysis of patients' heart rate variability (HRV), in concert with the other abovementioned parameters, the investigators seek to forward the development of novel mathematical models and tools for on-line detection of cardiovascular and autonomic dysfunction in the perioperative setting.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Patients undergoing non-cardiac surgery under general anesthesia * Patients aged 18-80 years * Patients who are capable of giving informed consent

Exclusion criteria

* Patients \<18 or \>80 years of age * Patients with an active cardiac pace maker * Patients with an absent sinus rhythm in ECG * Patients presenting with a preexisting arrhythmia * Patients requiring postoperative ICU therapy * Patients with pheochromocytoma

Design outcomes

Primary

Measure	Time frame	Description
Heart rate variability	During and immediately subsequent to surgery performed under general anesthesia	The analysis of heart rate variability (HRV) has been used to assess autonomic nervous system responses to therapeutic interventions, and to quantify risk in a wide variety of both cardiac and non-cardiac disorders when combined with other diagnostic tests - though HRV analysis has seen its greatest cardiologic use in post-myocardial infarction risk stratification and in assessing risk for arrhythmic events. HRV analysis has become widespread and relatively simple to perform - however, until now, these analyses have not been performed in detail in the perioperative period.

Countries

Austria

Outcome results