BEACON Care ® System Assisting Ventilation in Pressure Support Ventilation (PSV) Patient

Evaluation of Beacon Care System Advice in Pressure Support: Does the System Maintain Patients Within Appropriate Levels of Support?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02760147

Acronym

BEACON3

Enrollment

Registered

2016-05-03

Start date

2015-07-31

Completion date

2017-03-31

Last updated

2018-05-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial Respiration

Keywords

Pressure Support Ventilation

Brief summary

The aim of this study is to evaluate the ventilator settings advice given by the BEACON care system in fitting with best level of support in patient under mechanical ventilation in Pressure Support mode.

Detailed description

The purpose of this study is to evaluate whether pressure support settings suggested by the B3 system and pressure support as well as Positive End Expiratory Pressure (PEEP) settings suggested by the B5 system, i.e. balancing under and over support based upon physiological models and simple clinical measures, are consistent with keeping patients within appropriate levels of support as assessed by the ratio between airwaiy pressure generated by the respiratory muscles (Pmus) and the maximum inspiratory pressure (MIP) (Pmus/MIP), the ratio between the inspiratory time (TI) and total respiratory time (TTOT) (TI/TTOT) and the Tension-Time index (TTi), these being obtained using less frequently used esophageal catheter measurements.

Interventions

DEVICEPressure Support Over Support

Pressure Support Level upward by 50%, 2 hours

DEVICEPressure Support Under Support

Pressure Support Level downward by 50%, 2 hours

DEVICEPEEP Over Level

PEEP Level upward by 50%, 2 hours

DEVICEPEEP Under Level

PEEP Level downward by 50%, 2 hours

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Under mechanical ventilation in Pressure Support mode

Exclusion criteria

* Neuromuscular impairment

Design outcomes

Primary

Measure	Time frame	Description
Reduction of respiratory fatigue of patient under mechanical ventilation	Average of 1 hour	Esophageal catheter will be positioned and pressure generated by the respiratory muscles will be measured to detect respiratory muscles' fatigue.

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026