Disorders of Consciousness
Conditions
Keywords
vegetative state, minimally conscious state, music, preference
Brief summary
Preferred music improves cognitive function in patients with disorders of consciousness (DOC). However, it is still unknown whether it is a general effect of music (because of its acoustic features) or an autobiographical effect (because of its emotional and meaningful contents). The aim of the present study was to investigate the effect of sensory modality (auditory versus olfactory) and preference (preferred versus neutral) of the testing context on the performance of four items from the coma recovery scale-revised
Interventions
BEHAVIORALsounds and odors
presentation of sounds and odors
Sponsors
Hospices Civils de Lyon
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Disorders of consciousness (Traumatic brain injury, stroke or anoxic encephalopathy) * Coma diagnosis (Plum and Posner, 1966), vegetative state (Task Force, 1994) or minimally conscious state (Giacino, Ashwal et al. 2002) * Lack of autonomic crisis since one week minimum * Medical condition considered stable * Patients who do not present hearing loss. Peaks I and II of Brainstem Auditory Evoked Potentials (BAEP) will be normal.
Exclusion criteria
* Hearing Problem * Uncontrolled Epilepsy * Autonomic crises * Medical unstable state * Pregnant or likely to be (interrogation data) or breastfeeding woman
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cognitive Function measured using the Coma Recovery Scale | within the first 30 days | Improvement of the score following sound stimuli and/or preferred stimuli |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Reaction time | within the first 30 days | Faster reaction following sound stimuli and/or preferred stimuli |
Countries
France
Outcome results
None listed