Attention Deficit Hyperactivity Disorder
Conditions
Keywords
Electroencephalography, Attention
Brief summary
The purpose of this study is to refine a new assessment tool for Attention Deficit/Hyperactivity Disorder (ADHD) and then to test its validity (i.e. ability to discriminate between individuals with ADHD and healthy controls.
Detailed description
The purpose of this study is to build upon the success the novel approach and software for analyzing electroencephalography (EEG) data to identify biomarkers of ADHD in adults by further refining the method. Then to test the ability of this new assessment tool to differentiate between adults with ADHD and healthy controls by comparing the classification accuracy of the metrics from the new tool to the classification accuracy of existing behavioral tests for ADHD.
Interventions
OTHERNAT electroencephalography (EEG) test
Individuals in both groups are asked to perform standard behavioral tests and an electroencephalography (EEG) test.
Sponsors
University of California, Los Angeles
University of California, Berkeley
Oregon Health and Science University
National Institute of Mental Health (NIMH)
Think Now Incorporated
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
Specific inclusion criteria for ADHD are: 1. meet established Diagnositic and Statistical Manual-5 criteria for ADHD predominately inattentive or combined subtype with clinically significant levels of impairment, diagnosed by structured clinical interview, the Mini International Neuropsychiatric Interview, and corroborating information 2. Clinical Global Impression-Severity (CGI-S) score ≥ 4 for ADHD 3. no lifetime history of DSM-5 bipolar disorder, psychotic disorder, pervasive developmental disorder, obsessive-compulsive disorder, substance abuse, or substance dependence (except nicotine) as assessed with the Mini International Neuropsychiatric Interview (MINI). 4. able in the opinion of the investigator to complete all required study procedures.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| NAT Slow Fluctuation Test and Retest to assess change for Test Replicability | A single measurement is made for each individual at DAY 1 - the time of the brain wave (EEG) test; and a single measure is made again in each individual at least 30 days later (DAY 2) to identify any differences, to assess replicability of the measure. | The NAT EEG test simultaneously generates 2 EEG values and 1 behavioral value that are used together as an assessment metric for ADHD. This is a one-time measure to assess its magnitude in ADHD vs Control. |
Countries
United States
Outcome results
None listed