Chronic Kidney Disease on Hemodialysis
Conditions
Keywords
heart rate variability
Brief summary
This study assesses autonomic nervous system function by power spectral analysis of RR interval dynamics in ultrafiltration subjects without blood pressure variation.
Detailed description
Variations over time in autonomic nervous activity due to differences in ultrafiltration rate will be evaluated by measuring heart rate variability in hemodialysis patients without blood pressure variations during HD session. The subjects will be divided into 3 groups, those with UFR \< 10 ml/hr/kg; ≥10 ml/hr/kg but ≤ 15 ml/hr/kg; and \>15 ml/hr/kg, and Holter ECG are recorded continuously during HD session using frequency analysis of RR intervals.
Interventions
OTHERAnalysis of the holter electrocardiogram
Sponsors
University of Hyogo
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
No minimum to 1 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients with stable undergoing hemodialysis without hanging in blood pressure during hemodialysis.
Exclusion criteria
* Patients with chronic atrial fibrillation * Patients with frequent ventricular premature beats * Patients with a permanent pacemaker * Patients with taking antihypertensive drugs * Patients with medical treatment due to changes in blood pressure
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The outcome measures was low frequency power (LF, ms2) to high frequency power (HF, ms2) ratio (LF/HF ratio) of heart rate variability. The three subject groups with difference ultrafiltration were compared by LF/HF ratio during hemodialysis session. | 4 hours | Variations over time in autonomic nervous activity due to differences in ultrafiltration rate will be evaluated by measuring heart rate variability. |
Countries
Japan
Outcome results
None listed