Postoperative Pain
Conditions
Brief summary
The infiltration of the surgical wound is an effective strategy for postoperative analgesia. Nonsteroidal antiinflammatories are useful in this way. Objective: To compare the analgesic effectiveness of diclofenac sodium, bupivacaine or bupivacaine plus diclofenac sodium infiltrating wound appendectomies. Method: Comparative, double blind, American Society Anesthesiologist classification I-II,18-65años. Group 1 (Bupivacaine n = 14), Group 2 (Diclofenac Sodium n = 14), Group 3 (Bupivacaine + Diclofenac Sodium n = 15). Pain at rest and dynamic, rescue analgesic consumption in Post Anesthesia Care Unit (PACU) and 24 hours after surgery were evaluated.
Interventions
DRUGBupivacaine
DRUGSodium diclofenac
Sponsors
Hospital Central Dr. Luis Ortega
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* American Society Anesthesiologist I- II * aged 18 and 65 * both sexes * patients diagnosed with acute appendicitis operated under general anesthesia
Exclusion criteria
* Patients known to any allergy of the drugs used in the study * Different incision approach Mc Burney * Some intraoperative surgical complications * Pregnant patients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| rest and dynamic postoperative pain with visual analogue scale | 24 hours of postoperative period | — |
| rescue analgesic consumption | 24 hours of postoperative period | — |
| appearance of bowel sounds | 24 hours of postoperative period | auscultation of bowel sounds |
| changes in rest and dynamic postoperative pain with visual analogue scale | 24 hours of postoperative pain | — |
Secondary
| Measure | Time frame |
|---|---|
| number of participants with skin suture removal after 10 days | 10 days of postoperative pain |
Outcome results
None listed