Oligoasthenoteratozoospermia
Conditions
Keywords
Oligoasthenoteratozoospermia, Male factor managment, Intacytoplasmic sperm injection
Brief summary
This study is the first to evaluate the effect of oral supplementation with antioxidants combined with lifestyle modification for severe male factor partner of couples undergoing ICSI.
Detailed description
Patients underwent a therapy of a three-month period of treatment with either oral L-carnitine only (2g daily) or oral carnitine (2g daily) combined with modifiable lifestyle factors.
Interventions
OTHERAntioxidant (l-cratinine) + modifiable lifestyle factors
All participants were subjected to the same three-month period treatment protocol, which included 1) antioxidant treatment with L-Carnitine (2g daily); 2) frequent ejaculation every 2 days; and 3) minimizing adverse lifestyle factors.
Sponsors
Benha University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 39 Years
Healthy volunteers
No
Inclusion criteria
* Long protocol for ovulation * Oligoasthenoteratozoospermic male partner ( (count \< 0.5 million/ml, Motility=\< 40% Progressive motility =\<10 %, Abnormal forms \>99%). * Fresh semen samples.
Exclusion criteria
* Day 3 embryo transfer * Incomplete ICSI cycles * Endometrial thickness\> 7mm
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate | two weeks |
| Implantation rate | one month |
Countries
Egypt
Contacts
Primary ContactSalah Elbashir, M.Sc
Backup ContactYasmin Magdi, M.Sc
Outcome results
None listed