Effect of Infraorbital and Infratrochlear Nerve Block on Emergence Agitation in Patients Undergoing Septorhinoplasty

Effect of Infraorbital and Infratrochlear Nerve Block on Emergence Agitation in Patients Undergoing Septorhinoplasty: A Randomized Controlled Trial

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02751268

Enrollment

Registered

2016-04-26

Start date

2016-04-30

Completion date

2017-03-31

Last updated

2016-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergence Agitation, Pain

Keywords

infraorbital nerve block, infratrochlear nerve block, septorhinoplasty, general anesthesia, postoperative analgesia

Brief summary

The purpose of this study is to determine whether bilateral infraorbital and infratrochlear nerve block in patients undergoing septorhinoplasty are effective in preventing emergence agitation.

Detailed description

Emergence agitation is a postanesthetic phenomenon characterized as confusion, disorientation and violent behavior. Although its etiology is not well understood, risk factors associated with the condition include pain and ENT (ear, nose and throat) surgery. Bilateral infraorbital and infratrochlear nerve block in patients undergoing septorhinoplasty is effective in treating postoperative pain. The investigators have designed this study to evaluate the effect of infraorbital and infratrochlear nerve block on emergence agitation in patients undergoing septorhinoplasty.

Interventions

DRUGNormal Saline

Bilateral infraorbital and infratrochlear nerve block before general anesthesia with normal saline

DRUGRopivacaine

Bilateral infraorbital and infratrochlear nerve block before general anesthesia with 0.5% ropivacaine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Septorhinoplasty * American Society of Anesthesiologists (ASA) classification I-II * Written informed consent

Exclusion criteria

* ASA classification greater than III * Allergy to ropivacaine * Incapability to give consent * Chronic pain * Coagulopathy

Design outcomes

Primary

Measure	Time frame	Description
Emergence agitation	2 hours after surgery	Emergence agitation is measured by Riker Sedation-Agitated Scale (RASS) and is defined as RASS=5-7

Secondary

Measure	Time frame	Description
Pain intensity	2, 8, 24, 48 hours after surgery	0-10 numerical rating scale (NRS) : from 0 = no pain to 10 = worst pain imaginable
Patient satisfaction	48 hours after surgery	1-5 scale (1: very unsatisfactory, 2: rather unsatisfactory, 3: fair, 4: rather satisfactory, 5: very satisfactory)

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026