Congenital Cataract
Conditions
Keywords
Congenital cataracts, Opacity location, Opacity shape, Classification, Clinical applicability
Brief summary
Photography is considered as one of the most important means to promote evidence-based medical practice in pediatric ophthalmology.This study is to investigate the feasibility of congenital cataract morphological classifications and monitoring using slit-lamp-adapted anterior segmental photography in a large cohort that included uncooperative children.
Detailed description
Lens opacities in congenital cataracts have a wide range of presentations.Therefore, it is important to find a method of recording, classifying and monitoring cataract morphologies that is feasible and safe in a large cohort of children with congenital cataracts, including uncooperative children. Photography is considered as one of the most important means to promote evidence-based medical practice in pediatric ophthalmology. In this study, the investigators studied congenital cataract morphological classifications and monitoring using slit-lamp-adapted anterior segmental photography and evaluated its safety and feasibility in pediatric cataract patients registered in the Childhood Cataract Program of the Chinese Ministry of Health.
Interventions
PROCEDUREslit-lamp-adapted anterior segmental photography
The eligible patients underwent pupil dilation and slit-lamp-adapted anterior segmental photography to electronically record and monitor the morphology of their cataractous lens.
Sponsors
Ministry of Health, China
Sun Yat-sen University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
No minimum to 10 Years
Healthy volunteers
No
Inclusion criteria
* Children with pediatric unilateral/bilateral cataracts * Children who were younger than 10 years of age
Exclusion criteria
* Premature birth * Microphthalmia * Micro-or Megalocornea * Keratoconus * Glaucoma * Traumatic or complicated cataracts * Vitreous and retinal diseases * Any previous surgeries, and contraindication for pupil dilation and sedation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Congenital Cataract Morphological Classifications and Monitoring using Slit-Lamp-Adapted Photography | baseline | All eligible pediatric patients underwent pupil dilation with compound tropicamide eye drops 3 times (1 time every 10 minutes) before the examination or administration of sleep aid medicine. Then, the children underwent slit-lamp-adapted anterior segmental photography (BX900, Haag-Streit AG, Köniz, Switzerland) for each cataractous lens, including one diffuse light photo, one slit-light photo across the cataract and one retro-illumination photo. All photos of the included patients were screened and morphologically classified separately by two pediatric ophthalmologists; a third ophthalmologist was masked and required to make a decision if the first two physicians had different opinions. |
Countries
China
Outcome results
None listed