Paravertebral Block (PVB) Combined Pectoral Musculature Blocks for Modified Radical Mastectomy (MRM)

Comparisons the Analgesia of Paravertebral Block Combined With Thoracic Wall Block Versus Paravertebral Block Alone for Modified Radical Mastectomy in Breast Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02747992

Enrollment

100

Registered

2016-04-22

Start date

2015-10-31

Completion date

Unknown

Last updated

2016-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mastectomy, Modified Radical

Brief summary

Previous studies have shown that PVB reduces pain and postoperative nausea and vomiting after breast cancer surgery when used in addition to general anesthesia or sedation. However, major breast cancer surgery involves areas beyond the breast tissue, such as pectoral musculature.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 75 Years

Healthy volunteers

Inclusion criteria

* The American Society of Anesthesiologists (ASA) Physical Status classification I to III * 20 - 75 years of age * female gender

Exclusion criteria

* body mass index (BMI) ≥ 35 kg/m2 * modified radical mastectomy not performed by the single surgeon (Ben Long Yu) * anesthesia not performed by the single anesthesiologist (Nai Liang Li)

Design outcomes

Primary

Measure	Time frame	Description
intraoperative sedation requirement	during operation	target controlled infusion (TCI) propofol driven by the Schnider model in effect site control titrated to reach conscious sedation defined as Observer Assessment of Alertness/Sedation score of 2 to 3

Secondary

Measure	Time frame
time to first request of analgesics	postoperative 12 hours
postoperative analgesic requirement	postoperation to discharge
side effects	postoperation to within 24 hours after discharge

Outcome results