The Relationship Between the Flow of Arteriovenous Fistula and Cardiac Function in Haemodialysis Patients

Study of Access Flow ,Access Recirculation of Arteriovenous Fistula and the Relationship With Cardiac Function

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02747966

Enrollment

100

Registered

2016-04-22

Start date

2009-04-30

Completion date

2012-04-30

Last updated

2016-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complication of Hemodialysis

Keywords

access flow, access recirculation, cardiac output, cardiac index, hemodialysis

Brief summary

A prospective longitudinal surveillance for a period of 2 months. Sample - identify suitable Chronic Kidney Disease (CKD) patients who undergo HD with functioning AVF. Participants at various age range and both sexes are recruited to observe their access flow, access recirculation and cardiac function and assess their relationship.

Detailed description

All patients recruited who met the inclusion criteria were investigated access flow, access recirculation and cardiac function(including cardiac output,cardiac index,central blood volume,et al).Measurement time is the beginning of HD session (first 30min to 1 hr),Middle of HD session (optional),and the end of the HD session (1hr to 30 min prior to end of session). The follow-up duration is 6 months and 12 months.Repeat the assessment at the above time points.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

16 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Patients undergo HD with native AVF * AF of AVF between 300ml/min and 1800ml/min

Exclusion criteria

* Patients whose AVF developed Access Recirculation (AR) which cannot be resolved at the time of measurement * Patients developed access or systemic infection during the study period

Design outcomes

Primary

Measure	Time frame
to access the chang of the fistula blood flow in HD patients using Ultrasound Dilution method	Change of the fistula blood flow from baseline to 6 months

Secondary

Measure	Time frame
Changes of the Cardiac Index (CI) during the course of hemodialysis therapy	from baseline to 6 months
Changes of the Oxygen delivery ( Adequacy of hemoglobin level to Epoetin) during the course of hemodialysis therapy	from baseline to 6 months

Countries

China

Outcome results