Leucine Supplementation in Young Subjects Undergoing Resistance Training

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02744443

Enrollment

Registered

2016-04-20

Start date

2015-01-31

Completion date

2016-04-30

Last updated

2016-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Volunteers

Brief summary

Leucine supplementation could be useful to support muscle anabolism. This study aims to investigate the effects of leucine supplementation on muscle mass and muscle strength in young subjects undergoing resistance training.

Interventions

DIETARY_SUPPLEMENTLeucine

DIETARY_SUPPLEMENTPlacebo

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

MALE

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* training experience \> 12 months * no previous use of anabolic steroids * no diagnosed diseases or injuries at the time of recruitment * one-maximum repetition strength (1-RM) in leg press ≥ 3.5 and ≤ 5.0 times the body weight

Exclusion criteria

* use of creatine or beta-alanine supplements for the last 3 months * use of protein or aminoacids supplements for the last 1 month * engagement in specific dietary restrictions * engagement in competitive sports

Design outcomes

Primary

Measure	Time frame	Description
muscle cross-sectional area	12 weeks	B-mode ultrasound

Secondary

Measure	Time frame	Description
muscle strength	12 weeks	One repetition maximum (1RM) on 45º leg press machine and Muscular Endurance Test on 45º leg press machine

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026