Anesthesia
Conditions
Keywords
electroencephalogram, hemodynamic monitoring, respiratory monitoring
Brief summary
The present study is designed to validate an multimodal indicator of anesthetic depth (Schneider G et al. 2014, Anesthesiology 120, 819-28). The indicator previously developed shall now be tested on an independent set of data. The investigators will include 250 patients undergoing general anesthesia in 3 German tertiary care centers. The design is strictly observational - the anesthetic regime is at the discretion of the clinician and will not be influenced.
Interventions
the study is observational
Sponsors
Technical University of Munich
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age ≥ 18 years * elective surgery under general anesthesia * anticipated operating time of about one hour or longer * ASA physical status I-III * written informed consent
Exclusion criteria
* chronic intake of CNS affecting drugs * alcohol or drug abuse in the last three months * CNS or psychiatric disease * hardness of hearing or deafness * abnormal gastrointestinal motility * non-adherence to fasting guidelines, emergency surgery * anticipated difficult airway * pregnancy * cardiac surgery and surgery involving the head and/or neck * postoperatively prolonged intubation * pre- and/or postoperative intensive care treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ability of the multimodal indicator of anesthetic depth to discriminate between consciousness and unconsciousness | 1 minute |
Secondary
| Measure | Time frame |
|---|---|
| the indicator's ability to discriminate between consciousness, surgical anesthesia and deep anesthesia | 1 minute |
Countries
Germany
Outcome results
None listed