Premolar Autotransplantation in Juvenile Dentition: Quantitative Assessment of Vertical Bone and Soft Tissue Growth

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02740907

Enrollment

Registered

2016-04-15

Start date

2012-08-31

Completion date

2014-10-31

Last updated

2016-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Aplasia, Traumatic Dental Injury

Brief summary

Objective: Premolar autotransplantation represents an effective therapeutic option for the treatment of juvenile dentition in traumatic dental injury with tooth loss. Numerous studies report on the osteoinductive potency of the method, however, to date no quantitative data has been provided. The objective of this prospective clinical study was to quantitatively assess the bone and soft tissue levels after autogenous premolar transplantation by clinical and radiographic parameters. Materials/Methods: In the study 26 premolars were transplanted in 20 patients after traumatic dental injury (n=10) or tooth aplasia (n=16) in the upper front. Standard clinical parameters were evaluated. Based on a standardized photo documentation, the relative soft tissue level was measured in comparison to the healthy adjacent teeth. Radiographic findings involved the evaluation of root resorption, pulp canal obliterations and the relative bone height. Patient satisfaction was determined using a standardized questionnaire.

Interventions

PROCEDUREpremolar autotransplantation

Autogenous tooth transplantation of premolars to the anterior maxilla to stimulate bone and soft tissue growth.

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

10 Years to 17 Years

Healthy volunteers

Inclusion criteria

* premolar transplantation after tooth loss in the anterior maxilla (13-23) by aplasia or trauma

Design outcomes

Primary

Measure	Time frame	Description
Transplant survival	2006-2014	Evaluation by Kaplan-Meier-Estimator.
Soft tissue development	2006-2014	Measurement by standardized clinical documentation.
Bone development	2006-2014	Measurement by radiographic evaluation.
Sensibility	2006-2014	Assessment of clinical sensibility.
Root resorptions	2006-2014	Radiographic evaluation.
Pulp obliteration	2006-2014	Radiographic evaluation.

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026