Pulmonary Disease, Scleroderma, Systemic, Sleep Apnea, Obstructive
Conditions
Keywords
scleroderma, sleep apnea, pulmonary disease
Brief summary
Scleroderma is an autoimmune disease with skin manifestations and may have pulmonary involvement. Obstructive sleep apnea (OSA) may also be seen in scleroderma. Less is known regarding the prevalence of OSA in scleroderma and its association with pulmonary involvement.
Detailed description
Scleroderma is an autoimmune disease with skin manifestations and may have pulmonary involvement. OSA may also be seen in scleroderma. Less is known regarding the prevalence of obstructive sleep apnea in scleroderma and its association with pulmonary involvement. The investigators would like to address the prevalence of OSA in patients with Scleroderma, using overnight cardiorespiratory polygraphy. Other comorbidities and pulmonary findings on computer tomography (CT) as well as lung function tests will be evaluated. The investigators plan to include 60 patients.
Interventions
OTHERNo intervention
Observational study. Intervention according to the clinical routines (not included in this part)
Sponsors
Marmara University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Known scleroderma diagnosis * Must be able to give informed consent
Exclusion criteria
* Serious neurological and/or psychiatric disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of OSA defined by apnea-hypopnea index (AHI) of at least 15/h on the overnight sleep study | 6 months | All participants will be evaluated within 6 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of pulmonary involvement based on computer tomography findings | 6 months | All patients will be evaluated within 6 months |
Countries
Turkey (Türkiye)
Outcome results
None listed