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The Role of Oxytocin in Modulating the Effects of Social Feedback on Achieving Personal Goals

Status
Completed
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02740101
Enrollment
62
Registered
2016-04-15
Start date
2014-11-30
Completion date
2015-10-31
Last updated
2017-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

oxytocin, social reward, social punishment

Brief summary

To examine potential differential effects of receiving various social feedback on achieving personal goals,and whether oxytocin would modulate these effects.

Detailed description

In the present study, 62 healthy male participants participated in the double-blind, placebo-controlled experiment. Investigators aimed to test the idea that whether oxytocin would modulate subjective responses during receiving various social reward and social punishment about the future outcomes of pursuing personal goals.

Interventions

intranasal administration of oxytocin (40 IU)

DRUGplacebo treatment

intranasal administration of placebo (40 IU)

Sponsors

University of Electronic Science and Technology of China
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy subjects without past or current psychiatric or neurological disorders.

Exclusion criteria

* Taking oral contraceptives; * No history of head injury and medical or psychiatric illness.

Design outcomes

Primary

MeasureTime frameDescription
Rating of Encouragement after receiving specific social feedbackone hourThere're 96 different social feedback totally for four goals which were divided into four runs consisting of 24 different feedback separately for each goal video.Therefore,subjects were instructed to complete the encouragement rating after receiving each specific feedback. To measure the rating,the investigators used the 9-point likert scale in which one refers to the minimum encouragement while nine refers to maximum encouragement.

Secondary

MeasureTime frameDescription
Rating of Likeability after receiving specific social feedbackone hourThere're 96 social feedback totally for four goals which were divided into four runs consisting of 24 feedback separately for each goal video.Therefore,subjects were instructed to complete the likeability rating after receiving each specific feedback. To measure the rating,the investigators used the 9-point likert scale in which one refers to the minimum likeability while nine refers to maximum likeability.

Other

MeasureTime frameDescription
Rating of Confidence after receiving a series of social feedbackone hourThere're 96 social feedback totally for four goals which were divided into four runs consisting of 24 feedback separately for each goal video.Furthermore, these 24 feedback were categorized into three types which include 8 feedback separately.Therefore,subjects were instructed to complete the confidence rating after receiving these 8 feedback together. To measure the rating, the investigators used the 9-point likert scale in which one refers to the minimum confidence while nine refers to maximum confidence.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026