Comparing Pain Relief Between Exparel® Injection vs. On-Q Catheter as the Postsurgical Analgesia Following Total Knee Arthroplasty (TKA)

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02739230

Enrollment

Unknown

Registered

2016-04-15

Start date

2013-12-31

Completion date

Unknown

Last updated

2016-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis: Joint Replacement Surgery

Brief summary

The goal of this research project is to evaluate the effectiveness of a novel treatment to control pain after Total Knee Arthroplasty (TKA). The proposed approach to manage pain and eliminate risks associated with catheters is the use of Exparel injection into the joint at the time of surgery.

Interventions

DRUGExparel

DRUGOn-Q pain intra-articular catheter

Study design

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Adults scheduled to undergo primary total knee replacement 2. Willing and able to provide informed consent

Design outcomes

Primary

Measure	Time frame
Total Morphine and morphine equivalent consumption	96 hours post-op

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026