Anti-calculus Efficacy of a Dentrifice Containing Sodium Pyrophosphate and Potassium Pyrophosphate in Heavy Calculus Formers

Evaluation of Anti-calculus Efficacy of a Dentrifice Containing Sodium Pyrophosphate and Potassium Pyrophosphate in Heavy Calculus Formers

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02738541

Enrollment

Registered

2016-04-14

Start date

2015-08-31

Completion date

2016-02-29

Last updated

2016-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ANTICALCULUS EFFICACY OF PYROPHOSPHATE IN HEAVY CALCULUS FORMERS

Brief summary

The purpose of this study was to determine the anti-calculus effect of dentrifice containing 5% sodium pyrophosphate and potassium pyrophosphate in a triple-mask placebo controlled randomized clinical trial.

Interventions

DRUGDENTRIFICE CONTAINING 5% SODIUM AND POTASSIUM PYROPHOSPHATE

DENTRIFICE CONTAINING 5% SODIUM AND POTASSIUM PYROPHOSPHATE WAS ADVISED TWICE DAILY FOR 6 MONTHS

DRUGPLACEBO DENTRIFICE WITHOUT PROPHOSPHATE

PLACEBO DENTRIFICE WITHOUT PYROPHOSPHATE WAS ADVISED TWICE DAILY FOR 6 MONTHS

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

15 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

1. Age group 15-30 years. 2. Subjects who have not received periodontal therapy within preceding 1year. 3. Heavy calculus formers with simplified calculus index score 1.5-3 .

Exclusion criteria

1. Age group 15-30 years. 2. Subjects who have not received periodontal therapy within preceding 1year. 3. Heavy calculus formers with simplified calculus index score 1.5-3 .

Design outcomes

Primary

Measure	Time frame
simplied calulus index.	Baseline to 6 months

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026