Endometrioma
Conditions
Brief summary
Investigators compare ICSI results for endometrioma patients with or without cyst aspiration if more than 5cm &with or without GnRh agonists for all endometrioma patients
Detailed description
Group 1 consists of 30 patients of endometrioma more than 5cm subdivided into: Group 1A;Cyst aspiration followed by standard long protocol in 15 patients Group 1B;Cyst aspiration followed by GnRh suppression for 3 months then standard long protocol in 15 patients Group 2 consists of 30 patients of endometrioma less than 5cm subdivided into : Group 2A;no intervention to the cyst. Standard long protocol Group 2B;GnRh suppression for 3 months then standard long protocol
Interventions
PROCEDUREendometrioma aspiration
Transvaginal ultrasound guided aspiration
DRUGGnRh agonist ( Decapeptyl )
3 monthly doses of Decapeptyl 7.5mg intramuscular
PROCEDUREstandard long stimulation protocol
Decapeptyl 3.75mg in the mid luteal phase followed by human menopausal gonadotropins(HMG);fostimon, or merional injections after bleeding, doses are individualization according to each patient, monitored by follicular size &serum estradiol.
Sponsors
Kasr El Aini Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* endometrioma patients
Exclusion criteria
* Follicle stimulating hormone(FSH)10 or more * hydrosalpinx * GnRh suppression in the last 12 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients with urine pregnancy test positive 2 weeks after embryo transfer | 5 months |
Countries
Egypt
Outcome results
None listed