Correlation of Hepatitis C, Alcoholic Liver Disease, and Renal Failure With Hyperfibrinolysis in Liver Failure

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02737345

Enrollment

Registered

2016-04-13

Start date

2015-11-01

Completion date

2017-04-01

Last updated

2017-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cirrhosis

Keywords

fibrinolysis, liver transplant, thromboelastometry

Brief summary

1. Further characterize the incidence of hyperfibrinolysis in cirrhotics 2. Correlate hyperfibrinolysis with 1. hepatitis C 2. alcoholic liver disease 3. the subset of a&b with renal failure with and without dialysis 3. Better describe the hyperfibrinolytic ROTEM profile in cirrhotics

Interventions

OTHERRotem

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Be on the the liver transplant waiting list

Exclusion criteria

* liver failure without eligibility for transplant

Design outcomes

Primary

Measure	Time frame	Description
The percentage of patients who exhibit fibrinolysis	Within 60 minutes of sample run time	The percentage of patients who exhibit fibrinolysis, defined as a decrease in maximum clot firmness \<15% within 60 minutes of sample run time.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026